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Phospho-Axl (Y691) Polyclonal Antibody, 50ul Polyclonal Antibody Preparation It is an atypical calpain

SKU: 58032867674

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PLN162.00 PLN208.00

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Phospho-Axl (Y691) Polyclonal Antibody, 50ul Polyclonal Antibody Preparation It is an atypical calpainThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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Description

It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal| followed by two fibronectin type-III motifs

which encode negative regulatory proteins that prevent apoptotic cell death

It is involved in the control of several cellular processes by controlling the localization of cyclin B| MPAK| and MAPKAP kinase 2

MIM 613590) and BTN3 (e

Phospho-Axl (Y691) Polyclonal Antibody, 50ul Polyclonal Antibody Preparation It is an atypical calpainThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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