RJR-2403 - CAS# 15585-43-0 26481585 54(1):284-8

SKU: 20004228864

Pay in 4 interest-free payments of $27.50 Learn more

Live Spec

RJR-2403 - CAS# 15585-43-0 26481585 54(1):284-8Metanicotine, also known as RJR 2403 and TC 2403, is a neuronal nicotinic receptor agonist, showing high selectivity for the 42 subtype. Metanicotine has high affinity to rat brain cortex (Ki = 26 + 3 nM). Metanicotine is comparable to nicotine in activating rat thalamic synaptosomes (EC50 = 732 + 155 nM and Emax = 91 + 8% for RJR 2403; EC50 = 591 + 120 nM and Emax = 100 + 25% for nicotine) . Chronic administration of RJR 2403 in combination with low

Store: www.beecoms.com · Domain: www.beecoms.com